规格

价格

库存

数量

5 μg

¥ 428

6-8日内发货

10 μg

¥ 683

6-8日内发货

20 μg

¥ 1,130

5日内发货

50 μg

¥ 2,270

5日内发货

100 μg

¥ 4,430

5日内发货

200 μg

¥ 6,730

5日内发货

500 μg

¥ 13,800

5日内发货

1 mg

¥ 28,800

5日内发货

生物活性

产品描述	IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.62 kDa and the accession number is NP_001551.1.
生物活性	1.Loaded Recombinant Human IL-13 Protein, His Tag on HIS1K Biosensor, can bind Recombinant Human IL-13 R alpha 1/IL13RA1 Protein, hFc Tag (Cat#TMPY-06590) with an affinity constant of 21.200 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Loaded Recombinant Human IL13RA1 Protein (Fc Tag) (Cat#TMPY-06590) on ProA Biosensor, can bind Recombinant Human IL13 Protein (Cat#TMPY-01993) with an affinity constant of 17.6 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Recombinant Human IL-13 R alpha 1/IL13RA1 Protein, hFc Tag (Cat#TMPY-06590) captured on Protein A chip, can bind Avi-tag Biotinylated Recombinant Human IL-13 Protein, His & Avi Tag with an affinity constant of 74.900 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 4.Recombinant Human IL-13 R alpha 1/IL13RA1 Protein, hFc Tag (Cat#TMPY-06590) captured on Protein A chip, can bind Recombinant Human IL-13 Protein, His Tag with an affinity constant of 19.900 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 5.Recombinant Human IL-13 R alpha 1/IL13RA1 Protein, hFc Tag (Cat#TMPY-06590) captured on Protein A chip, can bind Avi-tag Biotinylated Recombinant Human IL-13 Protein, His & Avi Tag with an affinity constant of 74.900 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 6.Recombinant Human IL13RA1 Protein (Fc Tag) (Cat#TMPY-06590) captured on Protein A chip, can bind Recombinant Human IL13 Protein (Cat#TMPY-01993) with an affinity constant of 9.560 nM as determined in an SPR assay (Biacore T200) (Routinely tested).
研究背景	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	NP_001551.1
蛋白构建	A DNA sequence encoding the human IL13RA1 (NP_001551.1) (Met1-Thr343) was expressed with the fused Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gly 22
蛋白纯度	> 95 % as determined by SDS-PAGE.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, IL-13Ra, CD213A1
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	63.62 kDa (predicted); 81.81 kDa (reducing conditions)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)

IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)

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