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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LZTS2 Polyclonal Antibody

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货号 TMAB-08487

Anti-LZTS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LZTS2。Anti-LZTS2 Polyclonal Antibody 可用于 WB。

Anti-LZTS2 Polyclonal Antibody

Anti-LZTS2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08487

Anti-LZTS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LZTS2。Anti-LZTS2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-LZTS2 Polyclonal Antibody is a Rabbit antibody targeting LZTS2. Anti-LZTS2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
组织特异性Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景LAPSER1 is a member of the LZTS family. Due to its deletion in multiple cancers, including prostate tumors, LAPSER1 is purported to be a tumor suppressor. In cancer cell lines, the overexpression of LAPSER1 can lead to growth inhibition and colony-forming efficiency. LAPSER1 is highly expressed in testis and prostate, but can be detected at lower levels in spleen, thymus, uterus, small intestine and colon. LAPSER1 colocalizes with ?tubulin, MKLP-1 and p80 katanin. LAPSER1 is involved in cytokinesis. The disruption of LAPSER1, which is accompanied by the mislocalization of p80 katanin, results in malformation of the central spindle. This is a potential impetus for carcinogenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LZTS2
抗原种属
Human
基因名称
LZTS2
基因ID
84445
蛋白名称
Leucine zipper putative tumor suppressor 2
Uniprot ID
Q9BRK4
功能
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
化学信息
分子量Theoretical: 73 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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