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顶部生物活性储存和溶解信息计算器

Anti-UCHL1 Antibody (2X729)

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Anti-UCHL1 Antibody (2X729)
产品编号 TMAC-03180
别名 Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117

Anti-UCHL1 Antibody (2X729) 是一种 Rabbit 抗体，靶向 UCHL1。Anti-UCHL1 Antibody (2X729) 可用于 WB,ICC/IF,IHC,IP。

Anti-UCHL1 Antibody (2X729)

Anti-UCHL1 Antibody (2X729)

Rating icon 还可以
Anti-UCHL1 Antibody (2X729)
产品编号 TMAC-03180 别名 Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117

Anti-UCHL1 Antibody (2X729) 是一种 Rabbit 抗体，靶向 UCHL1。Anti-UCHL1 Antibody (2X729) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-UCHL1 Antibody (2X729) is a Rabbit antibody targeting UCHL1. Anti-UCHL1 Antibody (2X729) can be used in WB,ICC/IF,IHC,IP.
别名Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PGP9.5 on A549 cell lysates using anti-PGP9.5 antibody at 1/1,000 dilution.
2. ICC staining PGP9.5 in N2A cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining PGP9.5 in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500; IP: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景UCH-L1 (ubiquitin C-terminal hydrolase) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1-2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p13. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P09936
化学信息
分子量Theoretical: 25 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

ubiquitin thiolesteraseubiquitin carboxyl-terminal esterase L1PGP-95PGP 95PARK-5PARK 5HEL117HEL 117

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