BDCA-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 46.39 kDa and the accession number is Q8WTT0-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 3,100 | 5日内发货 | |
| 500 μg | ¥ 12,400 | 5日内发货 | |
| 1 mg | ¥ 20,700 | 5日内发货 |
| 生物活性 | Immobilized Human BDCA-2, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA. |
| 产品描述 | BDCA-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 46.39 kDa and the accession number is Q8WTT0-1. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | N-mFc |
| 蛋白编号 | Q8WTT0-1 |
| 别名 | HECL,DLEC,CLECSF7,CLECSF11,CLEC4C,CD303,BDCA-2,BDCA2 |
| 蛋白构建 | Phe46-Ile213 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
| 分子量 | 46.39 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 缓冲液 | Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 200 mM L-arginine (pH 8.5). |
| 存储 | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C after mAb labeling. |
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