Anti-DMP1 Antibody (6L12)

Name: Anti-DMP1 Antibody (6L12)
Brand: TargetMol
SKU: TMAY-02147
Rating: 4.5 (1 reviews)

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产品编号 TMAY-02147

Anti-DMP1 Antibody (6L12) 是一种 Rabbit 抗体，靶向 DMP1。Anti-DMP1 Antibody (6L12) 可用于 ELISA。

Anti-DMP1 Antibody (6L12)

还可以

产品编号 TMAY-02147

Anti-DMP1 Antibody (6L12) 是一种 Rabbit 抗体，靶向 DMP1。Anti-DMP1 Antibody (6L12) 可用于 ELISA。

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产品描述	Anti-DMP1 Antibody (6L12) is a Rabbit antibody targeting DMP1. Anti-DMP1 Antibody (6L12) can be used in ELISA.
Ig Type	Monoclonal Rabbit IgG
克隆号	6L12
交叉反应	Human
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Human DMP1 (rh DMP1; TMPY-02010; Q13316-1; Met1-Tyr513).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Dentin matrix acidic phosphoprotein (DMP1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. DMP1 contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation, DMP1 becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in DMP1 are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. DMP1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human DMP1 protein (TMPY-02010)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.