Ribavirin-13C5 (Standard)

Name: Ribavirin-13C5 (Standard)
Brand: TargetMol
SKU: TMSM-2041
Rating: 4.5 (1 reviews)

Synonyms: 利巴韦林-13C5 (标准品), Ribavirin-13C5 (标准品)

货号 TMSM-2041Cas号 1646818-35-0 一键复制产品信息

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Ribavirin-13C5 (Standard) is the standard form of Ribavirin-13C5,suitable for quantitative analysis,quality control,and related research in biochemical experiments. Ribavirin-13C5 is intended to be used as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin (T0684) is an antiviral guanosine nucleoside analog. 1,2 Once it enters cells,ribavirin is metabolized into an active triphosphate form that causes viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml). 3 Ribavirin (T0684)also reduces replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)in Vero cells (EC50 = 109.5 μM). 4 Aerosol administration of ribavirin (30 mg/kg)reduces mortality in a mouse model of influenza A infection.5Formulations containing ribavirin have been used in the treatment of respiratory syncytial virus (RSV),hepatitis C virus (HCV),and viral hemorrhagic fevers.

Ribavirin-13C5 (Standard)

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货号 TMSM-2041Cas号 1646818-35-0

别名 利巴韦林-13C5 (标准品), Ribavirin-13C5 (标准品)

规格	价格	库存	数量
1 mg	¥ 3,580	5日内发货

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产品介绍

生物活性

产品描述

Ribavirin-13C5 (Standard) is the standard form of Ribavirin-13C5, suitable for quantitative analysis, quality control, and related research in biochemical experiments. Ribavirin-13C5 is intended to be used as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin (T0684) is an antiviral guanosine nucleoside analog. 1,2 Once it enters cells, ribavirin is metabolized into an active triphosphate form that causes viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml). 3 Ribavirin (T0684) also reduces replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero cells (EC50 = 109.5 μM). 4 Aerosol administration of ribavirin (30 mg/kg) reduces mortality in a mouse model of influenza A infection.5Formulations containing ribavirin have been used in the treatment of respiratory syncytial virus (RSV), hepatitis C virus (HCV), and viral hemorrhagic fevers.

别名

利巴韦林-13C5 (标准品), Ribavirin-13C5 (标准品)

化学信息

分子量	249.17
分子式	C₈H₁₂N₄O₅
CAS No.	1646818-35-0
Smiles	NC(=O)c1ncn(n1)[13C@@H]1O[13C@H]([13CH2]O)[13C@@H](O)[13C@H]1O
密度	no data available

储存&溶解度

存储	Store at -80°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。