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Anti-S100P Antibody (6W876)

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Anti-S100P Antibody (6W876)
产品编号 TMAC-03676
别名 S100 calcium binding protein P, MIG9

Anti-S100P Antibody (6W876) 是一种 Rabbit 抗体,靶向 S100P。Anti-S100P Antibody (6W876) 可用于 WB,ICC/IF,IHC,IP。

Anti-S100P Antibody (6W876)

Anti-S100P Antibody (6W876)

Rating icon 还可以
Anti-S100P Antibody (6W876)
产品编号 TMAC-03676 别名 S100 calcium binding protein P, MIG9

Anti-S100P Antibody (6W876) 是一种 Rabbit 抗体,靶向 S100P。Anti-S100P Antibody (6W876) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-S100P Antibody (6W876) is a Rabbit antibody targeting S100P. Anti-S100P Antibody (6W876) can be used in WB,ICC/IF,IHC,IP.
别名S100 calcium binding protein P, MIG9
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-S100P antibody. Counter stained with hematoxylin.
2. ICC staining S100P in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining S100P in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景S-100 proteins are small dimeric members of the EF-Hand superfamily that participate in moderating intracellular calcium signals by binding to and regulating specific proteins in a calcium-dependent manner. S-100P is a survival factor that is associated with different types of tumors and can bind and regulate effector proteins. R1881, a synthetic androgen, regulates S-100P expression. S-100P interacts with a receptor for advanced glycation end products (RAGE) and activates it, thereby increasing the rates of cell growth, division, migration and invasion. This suggests that S-100P acts in an auto-crine manner through RAGE to trigger cell proliferation and survival. S-100P may also positively affect anchorage-independent growth to improve tumor formation. S-100P monomers strongly interact with one another, but not with other S-100 polypeptides, suggesting that homodimer formation is necessary for S-100P to function. The S-100P dimers are then stabilized by hydrophobic contacts.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 10 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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