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GABARAPL1 Protein, Human, Recombinant (His)

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货号 TMPY-03268

别名 GEC1, GABA(A) receptor-associated protein like 1, ATG8L, ATG8B, ATG8, APG8-LIKE, APG8L

ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient depletion or rapamycin treatment and leads to the response of more than 30 autophagy-related (ATG) genes known so far, including ATG8.

GABARAPL1 Protein, Human, Recombinant (His)
其他形式的 “GABARAPL1 Protein, Human, Recombinant (His)”:

GABARAPL1 Protein, Human, Recombinant (His)

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SPR兼容缓冲液
货号 TMPY-03268 别名 GEC1, GABA(A) receptor-associated protein like 1, ATG8L, ATG8B, ATG8, APG8-LIKE, APG8L

ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient depletion or rapamycin treatment and leads to the response of more than 30 autophagy-related (ATG) genes known so far, including ATG8.

规格价格库存数量
10 μg
¥ 94
6-8日内发货
20 μg
¥ 127
5日内发货
50 μg
¥ 208
5日内发货
100 μg
¥ 329
5日内发货
200 μg
¥ 519
5日内发货
500 μg
¥ 1,180
5日内发货
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产品介绍


生物活性
产品描述
ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient depletion or rapamycin treatment and leads to the response of more than 30 autophagy-related (ATG) genes known so far, including ATG8.
生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient depletion or rapamycin treatment and leads to the response of more than 30 autophagy-related (ATG) genes known so far, including ATG8.
种属
Human
表达系统
E. coli
标签N-His
蛋白编号Q9H0R8
蛋白构建A DNA sequence encoding the human GABARAPL1 (Q9H0R8) (Met1-Lys117) was expressed with a polyhistide tag at the N-terminus. Predicted N terminal: His
蛋白纯度
> 95 % as determined by SDS-PAGE
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名GEC1, GABA(A) receptor-associated protein like 1, ATG8L, ATG8B, ATG8, APG8-LIKE, APG8L
内毒素Please contact us for more information.
化学信息
分子量15.9 kDa (predicted); 20-22 kDa (reducing conditions)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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