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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IRF6 Antibody (1S582)

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货号 TMAB-07805

Anti-IRF6 Antibody (1S582) 是一种 Rabbit 抗体，靶向 IRF6。Anti-IRF6 Antibody (1S582) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-IRF6 Antibody (1S582)

Anti-IRF6 Antibody (1S582)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07805

Anti-IRF6 Antibody (1S582) 是一种 Rabbit 抗体，靶向 IRF6。Anti-IRF6 Antibody (1S582) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-IRF6 Antibody (1S582) is a Rabbit antibody targeting IRF6. Anti-IRF6 Antibody (1S582) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
1S582
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Translocates to nucleus in response to an activating signal.
组织特异性Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP).
抗原信息
免疫原
Recombinant Protein: human IRF6 protein, around C-terminal 150aa
抗原种属
Human
基因名称
IRF6
基因ID
3664
蛋白名称
Interferon regulatory factor 6
Uniprot ID
O14896
功能
Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation.
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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