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顶部生物活性储存和溶解信息计算器

Anti-ICAM-1/CD54 Antibody (7D308)

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产品编号 TMAY-03293

别名 P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2

Anti-ICAM-1/CD54 Antibody (7D308) 是一种 Rabbit 抗体，靶向 ICAM-1/CD54。Anti-ICAM-1/CD54 Antibody (7D308) 可用于 FCM,ICC/IF。

Anti-ICAM-1/CD54 Antibody (7D308)

Anti-ICAM-1/CD54 Antibody (7D308)

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Rating icon 还可以
产品编号 TMAY-03293 别名 P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2

Anti-ICAM-1/CD54 Antibody (7D308) 是一种 Rabbit 抗体，靶向 ICAM-1/CD54。Anti-ICAM-1/CD54 Antibody (7D308) 可用于 FCM,ICC/IF。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-ICAM-1/CD54 Antibody (7D308) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (7D308) can be used in FCM,ICC/IF.
别名P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2
Ig Type
Rabbit IgG
克隆号
7D308
交叉反应
Mouse
特异性
Mouse ICAM-1/CD54
验证活性
1. Flow cytometric analysis of Mouse ICAM1(CD54) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse ICAM1(CD54), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
2. Immunofluorescence staining of Mouse ICAM1 in Raw264.7 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-mouse ICAM1 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm and Cell membrane.
应用FCMICC/IF
推荐剂量
ICC-IF: 1:20-1:100; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ICAM-1 / CD54 (rM ICAM-1 / CD54; TMPY-01349; NP_034623.1; Met1-Asn485).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM-1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM-1 possesses binding sites for some immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM-1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease. Previous studies have shown that ICAM-1 is involved in inflammatory reactions and that a defect in ICAM-1 gene inhibits allergic contact hypersensitivity.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Mouse ICAM-1 / CD54 Protein (TMPY-01349)
抗原种属
Mouse
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

ICAM1ICAM 1CD-54CD 54BB-2BB 2

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