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Anti-LAG-3 Antibody-PE (6Z541)
还可以产品编号 TMAY-02828P
Anti-LAG-3 Antibody-PE (6Z541) 是一种 PE-conjugated Mouse 抗体，靶向 LAG-3。Anti-LAG-3 Antibody-PE (6Z541) 可用于 FCM。
Anti-LAG-3 Antibody-PE (6Z541)
Anti-LAG-3 Antibody-PE (6Z541)
还可以产品编号 TMAY-02828P
Anti-LAG-3 Antibody-PE (6Z541) 是一种 PE-conjugated Mouse 抗体，靶向 LAG-3。Anti-LAG-3 Antibody-PE (6Z541) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LAG-3 Antibody-PE (6Z541) is a PE-conjugated Mouse antibody targeting LAG-3. Anti-LAG-3 Antibody-PE (6Z541) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6Z541 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human LAG3 expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 72 hours with CD3 and CD28, then stained with PE-conjugated anti-Human LAG3. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μL/Test, 0.1 mg/mL |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells, and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | PE |
| 免疫原 | Recombinant Human LAG3 Protein |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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