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Anti-BCL10 Antibody (7U625) 是一种 Mouse 抗体,靶向 BCL10。Anti-BCL10 Antibody (7U625) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
Anti-BCL10 Antibody (7U625) 是一种 Mouse 抗体,靶向 BCL10。Anti-BCL10 Antibody (7U625) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
| 产品描述 | Anti-BCL10 Antibody (7U625) is a Mouse antibody targeting BCL10. Anti-BCL10 Antibody (7U625) can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG1, k |
| 克隆号 | 7U625 |
| 反应种属 | Human,Mouse |
| 应用 | WBIHC-PIHC-FrIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm > perinuclear region. Membrane raft. Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts. |
| 组织特异性 | Ubiquitous. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human BCL10 |
| 抗原种属 | Human |
| 基因名称 | BCL10 |
| 基因ID | |
| 蛋白名称 | B-cell lymphoma/leukemia 10 |
| Uniprot ID | |
| 功能 | Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1. |
| 分子量 | Theoretical: 26 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |