Name: CD16a (F176) Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00791
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 283

6-8日内发货

10 μg

¥ 446

6-8日内发货

20 μg

¥ 723

5日内发货

50 μg

¥ 1,380

5日内发货

100 μg

¥ 2,360

5日内发货

200 μg

¥ 4,280

5日内发货

500 μg

¥ 9,490

5日内发货

生物活性

产品描述	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is P08637-1.
生物活性	1. Immobilized Human Fc gamma RIIIA (F176) , His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Fc gamma RIIIA Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA. 2. Human Fc gamma RIIIA (F176) , His Tag captured on CM5 Chip via anti-His antibody can bind Rituximab, hFc Tag with an affinity constant of 0.92μM as determined in SPR assay.
研究背景	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	P08637-1
蛋白构建	Gly17-Gln208(F176)
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	IMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (F176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	24.7 kDa (predicted). Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD16a (F176) Protein, Human, Recombinant (His & Avi)

CD16a (F176) Protein, Human, Recombinant (His & Avi)

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