- 全部删除
- 您的购物车当前为空
Anti-IKBKA/IKBKB Antibody (6L571) 是一种 Rabbit 抗体,靶向 IKBKA/IKBKB。Anti-IKBKA/IKBKB Antibody (6L571) 可用于 WB,ICC/IF,IP。
Anti-IKBKA/IKBKB Antibody (6L571) 是一种 Rabbit 抗体,靶向 IKBKA/IKBKB。Anti-IKBKA/IKBKB Antibody (6L571) 可用于 WB,ICC/IF,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 7-10 days | |
100 μL | ¥ 2,485 | 7-10 days |
产品描述 | Anti-IKBKA/IKBKB Antibody (6L571) is a Rabbit antibody targeting IKBKA/IKBKB. Anti-IKBKA/IKBKB Antibody (6L571) can be used in WB,ICC/IF,IP. |
别名 | TCF16, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor, Nuclear factor NFkappaB inhibitor kinase alpha, Nuclear factor NF kappa B inhibitor kinase beta, Nuclear factor NF kappa B inhibitor kinase alpha, Nuclear Factor Kappa B Inhibitor Kinase alpha, NFKBIKB, NFKBIKA, MGC131801, Inhibitor of nuclear factor kappa B kinase subunit beta, Inhibitor of nuclear factor kappa B kinase beta subunit, Inhibitor Of Nuclear Factor Kappa B Kinase alpha Subunit, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells, Inhibitor of kappa light chain gene enhancer in B cells, IKKB, IKKalpha, IKKAI kappa B kinase 2, IKKA, IKK2, IKK1, IKK beta, IKK B, IKK alpha, IKK a kinase, IKK A, IKK 2, IKK 1, IkBKB, IKBKA, IkB kinase alpha subunit, IkappaB kinase, I kappa B kinase beta, I Kappa B Kinase alpha, I Kappa B Kinase 1, Conserved helix loop ubiquitous kinase, Conserved Helix Loop Helix Ubiquitous Kinase, CHUK1, CHUK |
Ig Type | IgG |
克隆号 | 6L571 |
交叉反应 | Human,Mouse,Rat |
应用 | ICC/IFIPWB |
推荐剂量 | WB: 1:1000; ICC/IF: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The transcription factor NFkB is retained in the cytoplasm in an inactive form by the inhibitory protein IkB. Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB. IkB kinase a (IKKa), previously designated CHUK, interacts with IkB-a and specifically phosphorylates IkB-a on Ser 32 and 36, the sites that trigger its degradation. IKKa appears to be critical for NFkB activation in response to proinflammatory cytokines. Phosphorylation of IkB by IKKa is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1. The functional IKK complex contains three subunits, IKKa, IKKb and IKKg (also designated NEMO), and each appear to make essential contributions to IkB phosphorylation. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 85/87 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容