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Anti-IKK- alpha/IKBKB Antibody (6L571)
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产品编号 TMAC-02124
别名 IKK2), IKBKB
Anti-IKK- alpha/IKBKB Antibody (6L571) 是一种 Rabbit 抗体，靶向 IKK- alpha/IKBKB。Anti-IKK- alpha/IKBKB Antibody (6L571) 可用于 WB,ICC/IF,IP。
Anti-IKK- alpha/IKBKB Antibody (6L571)
Anti-IKK- alpha/IKBKB Antibody (6L571)
还可以产品编号 TMAC-02124 别名 IKK2), IKBKB
Anti-IKK- alpha/IKBKB Antibody (6L571) 是一种 Rabbit 抗体，靶向 IKK- alpha/IKBKB。Anti-IKK- alpha/IKBKB Antibody (6L571) 可用于 WB,ICC/IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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| 产品描述 | Anti-IKK- alpha/IKBKB Antibody (6L571) is a Rabbit antibody targeting IKK- alpha/IKBKB. Anti-IKK- alpha/IKBKB Antibody (6L571) can be used in WB,ICC/IF,IP. |
| 别名 | IKK2), IKBKB |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | |
| 推荐剂量 | WB: 1:1000; ICC/IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The transcription factor NFkB is retained in the cytoplasm in an inactive form by the inhibitory protein IkB. Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB. IkB kinase a (IKKa), previously designated CHUK, interacts with IkB-a and specifically phosphorylates IkB-a on Ser 32 and 36, the sites that trigger its degradation. IKKa appears to be critical for NFkB activation in response to proinflammatory cytokines. Phosphorylation of IkB by IKKa is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1. The functional IKK complex contains three subunits, IKKa, IKKb and IKKg (also designated NEMO), and each appear to make essential contributions to IkB phosphorylation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 85/87 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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关键词
Serine/threonine protein kinase IKBKBNuclear factor NF-kappa-B inhibitor kinase β (NFKBIKB)Nuclear factor NF-kappa-B inhibitor kinase beta (NFKBIKB)Nuclear factor NF-kappa-B inhibitor kinase b (NFKBIKB)NFKBIKBInhibitor of nuclear factor kappa-B kinase subunit βInhibitor of nuclear factor kappa-B kinase subunit betaInhibitor of nuclear factor kappa-B kinase subunit bIKK-βIKKβIKK-betaIKK-BIKKBIKK-2IKK2I-kappa-B-kinase βI-kappa-B-kinase betaI-kappa-B-kinase bI-kappa-B kinase 2 (IKK-2
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