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Anti-human CD11a Antibody (6R990)

货号 TMAB-07384 一键复制产品信息
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Anti-human CD11a Antibody (6R990) 是一种 Mouse 抗体,靶向 human CD11a。Anti-human CD11a Antibody (6R990) 可用于 ICC/IF,FCM。

Anti-human CD11a Antibody (6R990)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07384

Anti-human CD11a Antibody (6R990) 是一种 Mouse 抗体,靶向 human CD11a。Anti-human CD11a Antibody (6R990) 可用于 ICC/IF,FCM。

Anti-human CD11a Antibody (6R990)
规格价格库存数量
100 μg
¥ 1,860
5日内发货
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产品介绍


生物活性
产品描述
Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.
Ig Type
Mouse IgG2b, k
克隆号
6R990
反应种属
Human
验证活性
1. Jurkat cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (human CD11a) monoclonal Antibody, Unconjugated (TMAB-07384) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Mouse IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei.
2. scatter diagram showing human peripheral blood leukocytes stained with human CD11a. The cells were incubated with the antibody (TMAB-07384) for 30 min at 22°C. The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed.
应用ICC/IFFCM
推荐剂量
ICC/IF: 1:100-500; FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Leukocytes.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4).
研究背景ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
基因名称
ITGAL
基因ID
蛋白名称
Integrin alpha-L
功能
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
化学信息
分子量Theoretical: 126 kDa. Actual: 180 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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