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Anti-human CD11a Antibody (6R990) 是一种 Mouse 抗体,靶向 human CD11a。Anti-human CD11a Antibody (6R990) 可用于 ICC/IF,FCM。
Anti-human CD11a Antibody (6R990) 是一种 Mouse 抗体,靶向 human CD11a。Anti-human CD11a Antibody (6R990) 可用于 ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 1,860 | 5日内发货 |
| 产品描述 | Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM. |
| Ig Type | Mouse IgG2b, k |
| 克隆号 | 6R990 |
| 反应种属 | Human |
| 验证活性 | 1. Jurkat cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (human CD11a) monoclonal Antibody, Unconjugated (TMAB-07384) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Mouse IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei. 2. scatter diagram showing human peripheral blood leukocytes stained with human CD11a. The cells were incubated with the antibody (TMAB-07384) for 30 min at 22°C. The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed. |
| 应用 | ICC/IFFCM |
| 推荐剂量 | ICC/IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Leukocytes. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4). |
| 研究背景 | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 基因名称 | ITGAL |
| 基因ID | |
| 蛋白名称 | Integrin alpha-L |
| 功能 | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. |
| 分子量 | Theoretical: 126 kDa. Actual: 180 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |