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Anti-Iba1 Antibody (3T586) 是一种 Mouse 抗体,靶向 Iba1。Anti-Iba1 Antibody (3T586) 可用于 ELISA。
Anti-Iba1 Antibody (3T586) 是一种 Mouse 抗体,靶向 Iba1。Anti-Iba1 Antibody (3T586) 可用于 ELISA。
产品描述 | Anti-Iba1 Antibody (3T586) is a Mouse antibody targeting Iba1. Anti-Iba1 Antibody (3T586) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2a |
克隆号 | 3T586 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IBA1 / AIF1 (rh IBA1 / AIF1; TMPY-03337; P55008-1; Met1-Pro147). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IBA1 / AIF1 protein (TMPY-03337) |
抗原种属 | Human |
研究领域 | Calcium-binding Proteins and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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