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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-AchE isoform H Polyclonal Antibody

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货号 TMAB-02231

Anti-AchE isoform H Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AchE isoform H。Anti-AchE isoform H Polyclonal Antibody 可用于 WB。

Anti-AchE isoform H Polyclonal Antibody

Anti-AchE isoform H Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02231

Anti-AchE isoform H Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AchE isoform H。Anti-AchE isoform H Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-AchE isoform H Polyclonal Antibody is a Rabbit antibody targeting AchE isoform H. Anti-AchE isoform H Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein. Isoform T: Nucleus. Note=Only observed in apoptotic nuclei. Isoform H: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
组织特异性Isoform H is highly expressed in erythrocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AchE isoform H
抗原种属
Human
基因名称
ACHE
基因ID
43
蛋白名称
Acetylcholinesterase
Uniprot ID
P22303
功能
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
化学信息
分子量Theoretical: 68 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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