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Anti-CH25H Polyclonal Antibody 2
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产品编号 TMAB-00422
Anti-CH25H Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CH25H。Anti-CH25H Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-CH25H Polyclonal Antibody 2
Anti-CH25H Polyclonal Antibody 2
还可以产品编号 TMAB-00422
Anti-CH25H Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CH25H。Anti-CH25H Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-CH25H Polyclonal Antibody 2 is a Rabbit antibody targeting CH25H. Anti-CH25H Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Human,Rat |
| 验证活性 | Sample: Lane 1: Human U-87 MG cell Lysates Primary: Anti-CH25H (TMAB-00422) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 32 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. |
| 免疫原 | KLH conjugated synthetic peptide: human CH25H |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Metabolism of lipids and lipoproteins,Cholesterol Metabolism,Oxidative Stress,Cholesterol Metabolism,Lipid metabolism,Oxidative stress |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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