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Anti-CH25H Polyclonal Antibody 2

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货号 TMAB-00422

别名 h25OH, EC 1.14.99.38, Cholesterol 25 monooxygenase, Cholesterol 25 hydroxylase, CH25H, C25H

Anti-CH25H Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 CH25H。Anti-CH25H Polyclonal Antibody 2 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-CH25H Polyclonal Antibody 2

Anti-CH25H Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-00422 别名 h25OH, EC 1.14.99.38, Cholesterol 25 monooxygenase, Cholesterol 25 hydroxylase, CH25H, C25H

Anti-CH25H Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 CH25H。Anti-CH25H Polyclonal Antibody 2 可用于 IF,IHC-Fr,IHC-P,WB。

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50 μL
¥ 1,165
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100 μL
¥ 1,965
5日内发货
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产品介绍


生物活性
产品描述
Anti-CH25H Polyclonal Antibody 2 is a Rabbit antibody targeting CH25H. Anti-CH25H Polyclonal Antibody 2 can be used in IF,IHC-Fr,IHC-P,WB.
别名h25OH, EC 1.14.99.38, Cholesterol 25 monooxygenase, Cholesterol 25 hydroxylase, CH25H, C25H
Ig Type
IgG
反应种属
Human,Rat
验证活性
Sample:
Lane 1: Human U-87 MG cell Lysates
Primary: Anti-CH25H (TMAB-00422) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kDa
Observed band size: 32 kDa
verifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CH25H
抗原种属
Human
基因名称
CH25H
基因ID
蛋白名称
Cholesterol 25-hydroxylase
Uniprot ID
研究领域
Metabolism of lipids and lipoproteins,Cholesterol Metabolism,Oxidative Stress,Cholesterol Metabolism,Lipid metabolism,Oxidative stress
功能
CH25H is involved in cholesterol and lipid metabolism and catalyses the formation of 25-hydroxycholesterol from cholesterol, leading to repression of cholesterol biosynthetic enzymes. It may play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing.
化学信息
分子量Theoretical: 32 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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