购物车
- 全部删除
您的购物车当前为空
Anti-DDR2 Antibody (1R524)
还可以产品编号 TMAY-03350
别名 TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
Anti-DDR2 Antibody (1R524) 是一种 Rabbit 抗体，靶向 DDR2。Anti-DDR2 Antibody (1R524) 可用于 ELISA。
Anti-DDR2 Antibody (1R524)
Anti-DDR2 Antibody (1R524)
还可以产品编号 TMAY-03350 别名 TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
Anti-DDR2 Antibody (1R524) 是一种 Rabbit 抗体，靶向 DDR2。Anti-DDR2 Antibody (1R524) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,279 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DDR2 Antibody (1R524) is a Rabbit antibody targeting DDR2. Anti-DDR2 Antibody (1R524) can be used in ELISA. |
| 别名 | TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167 |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1R524 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse DDR2 / CD167b (rM DDR2 / CD167b; TMPY-01728; NP_072075.2; Met1-Arg399). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2, up-regulates matrix metallloproteinase 1 (MMP-1) and MMP-2 expression in cellular matrix. DDR2/CD167b was found to recognise the triple-helical region of collagen X as well as the NC1 domain. Binding to the collagenous region was dependent on the triple-helical conformation. DDR2/CD167b autophosphorylation was induced by the collagen X triple-helical region but not the NC1 domain, indicating that the triple-helical region of collagen X contains a specific DDR2 binding site that is capable of receptor activation. DDR2/CD167b is induced during stellate cell activation and implicate the phosphorylated receptor as a mediator of MMP-2 release and growth stimulation in response to type I collagen. Moreover, type I collagen-dependent upregulation of DDR2/CD167b expression establishes a positive feedback loop in activated stellate cells, leading to further proliferation and enhanced invasive activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse DDR2 / CD167b Protein (TMPY-01728) |
| 抗原种属 | Mouse |
| 研究领域 | Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-DDR2 Antibody (1R524) | purchase Anti-DDR2 Antibody (1R524) | Anti-DDR2 Antibody (1R524) cost | order Anti-DDR2 Antibody (1R524)
嗨！有任何问题？点我咨询
评论内容