SRSF3 Protein, Human, Recombinant (GB1 & His)

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产品编号 TMPH-02086

SRSF3 Protein, Human, Recombinant (GB1 & His) is expressed in E. coli.

SRSF3 Protein, Human, Recombinant (GB1 & His)

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产品编号 TMPH-02086

SRSF3 Protein, Human, Recombinant (GB1 & His) is expressed in E. coli.

规格	价格	库存
5 μg	¥ 656	20日内发货
10 μg	¥ 1,070	20日内发货
20 μg	¥ 1,800	20日内发货
50 μg	¥ 2,730	20日内发货
100 μg	¥ 3,760	20日内发货
200 μg	¥ 5,780	20日内发货
500 μg	¥ 9,870	20日内发货
1 mg	¥ 16,000	20日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	SRSF3 Protein, Human, Recombinant (GB1 & His) is expressed in E. coli.
种属	Human
表达系统	E. coli
标签	N-6xHis-GB1
蛋白编号	P84103
别名	SRSF3,SRP20,Splicing factor, arginine/serine-rich 3,SFRS3,Serine/arginine-rich splicing factor 3,Pre-mRNA-splicing factor SRP20
氨基酸序列	MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKR
蛋白构建	1-86 aa
蛋白纯度	> 90% as determined by SDS-PAGE.
分子量	17.9 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export. RNA-binding is semi-sequence specific.