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Anti-CPT1A Polyclonal Antibody

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产品编号 TMAB-00474

别名 CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform

Anti-CPT1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CPT1A。Anti-CPT1A Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-CPT1A Polyclonal Antibody

Anti-CPT1A Polyclonal Antibody

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产品编号 TMAB-00474 别名 CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform

Anti-CPT1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CPT1A。Anti-CPT1A Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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生物活性
产品描述
Anti-CPT1A Polyclonal Antibody is a Rabbit antibody targeting CPT1A. Anti-CPT1A Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Paraformaldehyde-fixed, paraffin embedded Rat Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Mouse Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Ovarian Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
7. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane; Multi-pass membrane protein.
组织特异性Strong expression in kidney and heart, and lower in liver and skeletal muscle.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The mitochondrial oxidation of long-chain fatty acids is nitiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CPT1A
抗原种属
Human
基因名称
CPT1A
基因ID
1374
蛋白名称
Carnitine O-palmitoyltransferase 1, liver isoform
Uniprot ID
P50416
研究领域
Metabolism of lipids and lipoproteins,Metabolism,Fatty acids,Lipid metabolism,Mitochondrial markers,Fatty acid oxidation,Obesity,Lipid metabolism,Mitochondrial,Mitochondria
功能
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.
化学信息
分子量Theoretical: 86 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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