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Anti-CPT1A Polyclonal Antibody
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产品编号 TMAB-00474
别名 CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform
Anti-CPT1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CPT1A。Anti-CPT1A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-CPT1A Polyclonal Antibody
Anti-CPT1A Polyclonal Antibody
还可以产品编号 TMAB-00474 别名 CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform
Anti-CPT1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CPT1A。Anti-CPT1A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-CPT1A Polyclonal Antibody is a Rabbit antibody targeting CPT1A. Anti-CPT1A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| 疾病造模方案 | |
| 别名 | CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Paraformaldehyde-fixed, paraffin embedded Rat Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Mouse Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Ovarian Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. |
| 应用 | |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion outer membrane; Multi-pass membrane protein. |
| 组织特异性 | Strong expression in kidney and heart, and lower in liver and skeletal muscle. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | The mitochondrial oxidation of long-chain fatty acids is nitiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human CPT1A |
| 抗原种属 | Human |
| 基因名称 | CPT1A |
| 基因ID | |
| 蛋白名称 | Carnitine O-palmitoyltransferase 1, liver isoform |
| Uniprot ID | |
| 研究领域 | Metabolism of lipids and lipoproteins,Metabolism,Fatty acids,Lipid metabolism,Mitochondrial markers,Fatty acid oxidation,Obesity,Lipid metabolism,Mitochondrial,Mitochondria |
| 功能 | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism. |
| 分子量 | Theoretical: 86 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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