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Anti-PI 3 Kinase Class 3 Antibody (2W658)

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Anti-PI 3 Kinase Class 3 Antibody (2W658)
产品编号 TMAC-03286
别名 Vps34, Vps 34, PtdIns 3 kinase type 3, PK3C3, PIK3C3, PI3K type 3, PI3 kinase type 3, PI3 Kinase p100, phosphoinositide 3 kinase class 3, Phosphatidylinositol 3 kinase p100 subunit, Phosphatidylinositol 3 kinase class 3, Phosphatidylinositol 3 kinase catalytic subunit type 3, MGC61518, hVps34

Anti-PI 3 Kinase Class 3 Antibody (2W658) 是一种 Rabbit 抗体,靶向 PI 3 Kinase Class 3。Anti-PI 3 Kinase Class 3 Antibody (2W658) 可用于 WB,IHC。

Anti-PI 3 Kinase Class 3 Antibody (2W658)

Anti-PI 3 Kinase Class 3 Antibody (2W658)

Rating icon 还可以
Anti-PI 3 Kinase Class 3 Antibody (2W658)
产品编号 TMAC-03286 别名 Vps34, Vps 34, PtdIns 3 kinase type 3, PK3C3, PIK3C3, PI3K type 3, PI3 kinase type 3, PI3 Kinase p100, phosphoinositide 3 kinase class 3, Phosphatidylinositol 3 kinase p100 subunit, Phosphatidylinositol 3 kinase class 3, Phosphatidylinositol 3 kinase catalytic subunit type 3, MGC61518, hVps34

Anti-PI 3 Kinase Class 3 Antibody (2W658) 是一种 Rabbit 抗体,靶向 PI 3 Kinase Class 3。Anti-PI 3 Kinase Class 3 Antibody (2W658) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-PI 3 Kinase Class 3 Antibody (2W658) is a Rabbit antibody targeting PI 3 Kinase Class 3. Anti-PI 3 Kinase Class 3 Antibody (2W658) can be used in WB,IHC.
别名Vps34, Vps 34, PtdIns 3 kinase type 3, PK3C3, PIK3C3, PI3K type 3, PI3 kinase type 3, PI3 Kinase p100, phosphoinositide 3 kinase class 3, Phosphatidylinositol 3 kinase p100 subunit, Phosphatidylinositol 3 kinase class 3, Phosphatidylinositol 3 kinase catalytic subunit type 3, MGC61518, hVps34
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PI 3 Kinase Class 3 on C2C12 cells lysates using anti-PI 3 Kinase Class 3 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-PI 3 Kinase Class 3 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-PI 3 Kinase Class 3 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PI 3 Kinase Class 3 antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:1000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the 3' OH position of the inositol ring of inositol lipids. PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase, class III), is a member of the PI3/PI4-kinase family. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities are enhanced in the presence of magnesium, PI 3-kinase p100 activity is enhanced by manganese. Its activity can also be regulated by nutrients, suggesting an important role of PI-3 kinase p100 in the regulation of mTOR protein synthesis and autophagy.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 100 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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