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Anti-PI 3 Kinase Class 3 Antibody (2W658) 是一种 Rabbit 抗体,靶向 PI 3 Kinase Class 3。Anti-PI 3 Kinase Class 3 Antibody (2W658) 可用于 WB,IHC。
Anti-PI 3 Kinase Class 3 Antibody (2W658) 是一种 Rabbit 抗体,靶向 PI 3 Kinase Class 3。Anti-PI 3 Kinase Class 3 Antibody (2W658) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-PI 3 Kinase Class 3 Antibody (2W658) is a Rabbit antibody targeting PI 3 Kinase Class 3. Anti-PI 3 Kinase Class 3 Antibody (2W658) can be used in WB,IHC. |
别名 | Vps34, Vps 34, PtdIns 3 kinase type 3, PK3C3, PIK3C3, PI3K type 3, PI3 kinase type 3, PI3 Kinase p100, phosphoinositide 3 kinase class 3, Phosphatidylinositol 3 kinase p100 subunit, Phosphatidylinositol 3 kinase class 3, Phosphatidylinositol 3 kinase catalytic subunit type 3, MGC61518, hVps34 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of PI 3 Kinase Class 3 on C2C12 cells lysates using anti-PI 3 Kinase Class 3 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-PI 3 Kinase Class 3 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-PI 3 Kinase Class 3 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PI 3 Kinase Class 3 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the 3' OH position of the inositol ring of inositol lipids. PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase, class III), is a member of the PI3/PI4-kinase family. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities are enhanced in the presence of magnesium, PI 3-kinase p100 activity is enhanced by manganese. Its activity can also be regulated by nutrients, suggesting an important role of PI-3 kinase p100 in the regulation of mTOR protein synthesis and autophagy. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 100 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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