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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody

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货号 TMAB-10812

Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-HP1 alpha (Ser92)。Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody

Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10812

Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-HP1 alpha (Ser92)。Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HP1 alpha (Ser92). Anti-Phospho-HP1 alpha (Ser92) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome. Chromosome, centromere. Note=Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human HP1 alpha around the phosphorylation site of Ser92
抗原种属
Human
基因名称
CBX5
基因ID
23468
蛋白名称
Chromobox protein homolog 5
Uniprot ID
P45973
功能
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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