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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PTEN (Ser385) Polyclonal Antibody

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Anti-Phospho-PTEN (Ser385) Polyclonal Antibody
产品编号 TMAC-03457
别名 TEP1, PTEN1, PTEN (p-Ser385), PTEN (p-S385), p-PTEN (Ser385), p-PTEN (S385), Phospho-PTEN (S385), Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del

Anti-Phospho-PTEN (Ser385) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PTEN (Ser385)。Anti-Phospho-PTEN (Ser385) Polyclonal Antibody 可用于 IHC-P,IF(paraffin section),ELISA。

Anti-Phospho-PTEN (Ser385) Polyclonal Antibody

Anti-Phospho-PTEN (Ser385) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-PTEN (Ser385) Polyclonal Antibody
产品编号 TMAC-03457 别名 TEP1, PTEN1, PTEN (p-Ser385), PTEN (p-S385), p-PTEN (Ser385), p-PTEN (S385), Phospho-PTEN (S385), Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del

Anti-Phospho-PTEN (Ser385) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PTEN (Ser385)。Anti-Phospho-PTEN (Ser385) Polyclonal Antibody 可用于 IHC-P,IF(paraffin section),ELISA。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PTEN (Ser385) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTEN (Ser385). Anti-Phospho-PTEN (Ser385) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA.
别名TEP1, PTEN1, PTEN (p-Ser385), PTEN (p-S385), p-PTEN (Ser385), p-PTEN (S385), Phospho-PTEN (S385), Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del
Ig Type
IgG
交叉反应
Human,Mouse,Rat
应用
IHC-P
IF(paraffin section)
ELISA
推荐剂量
IHC-P: 1:100-300; ELISA: 1:5000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景phosphatase and tensin homolog(PTEN) Homo sapiens This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate ener
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human PTEN around the phosphorylation site of Ser385. AA range:370-400
抗原种属
human
Uniprot ID
P60484
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

PTEN (pSer385)PTEN (pS385)PTEN (phospho-Ser385)PTEN (phospho-S385)pPTEN (Ser385)pPTEN (S385)

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4个月前
5.0
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