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Anti-BRAF Monoclonal Antibody (3B686)

Synonyms: RAFB1, NS7, B-RAF1, BRAF1, B-raf
货号 TMAT-0179 一键复制产品信息
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Anti-BRAF Monoclonal Antibody (3B686) 是一种 Mouse 抗体,靶向 BRAF。Anti-BRAF Monoclonal Antibody (3B686) 可用于 WB,IHC,FCM。

Anti-BRAF Monoclonal Antibody (3B686)

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Rating icon 还可以
货号 TMAT-0179

别名 RAFB1, NS7, B-RAF1, BRAF1, B-raf

Anti-BRAF Monoclonal Antibody (3B686) 是一种 Mouse 抗体,靶向 BRAF。Anti-BRAF Monoclonal Antibody (3B686) 可用于 WB,IHC,FCM。

Anti-BRAF Monoclonal Antibody (3B686)
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产品介绍


生物活性
产品描述
Anti-BRAF Monoclonal Antibody (3B686) is a Mouse antibody targeting BRAF. Anti-BRAF Monoclonal Antibody (3B686) can be used in WB,IHC,FCM.
别名
RAFB1, NS7, B-RAF1, BRAF1, B-raf
Ig Type
IgG1
克隆号
3B686
反应种属
Human, Rat
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human BRAF (AA: 299-447) expressed in HEK293-6e.
抗原种属
Human
基因名称
BRAF
基因ID
蛋白名称
Serine/threonine-protein kinase B-raf
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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