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Anti-p73 Antibody (2O496)
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产品编号 TMAC-03036
别名 Tumor protein p73, TP73, P73_HUMAN, p53-related protein, p53-like transcription factor, p53 related protein, p53 like transcription factor, p 73
Anti-p73 Antibody (2O496) 是一种 Rabbit 抗体，靶向 p73。Anti-p73 Antibody (2O496) 可用于 WB,ICC/IF,IHC。
Anti-p73 Antibody (2O496)
Anti-p73 Antibody (2O496)
还可以产品编号 TMAC-03036 别名 Tumor protein p73, TP73, P73_HUMAN, p53-related protein, p53-like transcription factor, p53 related protein, p53 like transcription factor, p 73
Anti-p73 Antibody (2O496) 是一种 Rabbit 抗体，靶向 p73。Anti-p73 Antibody (2O496) 可用于 WB,ICC/IF,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-p73 Antibody (2O496) is a Rabbit antibody targeting p73. Anti-p73 Antibody (2O496) can be used in WB,ICC/IF,IHC. |
| 别名 | Tumor protein p73, TP73, P73_HUMAN, p53-related protein, p53-like transcription factor, p53 related protein, p53 like transcription factor, p 73 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse，Rat |
| 验证活性 | 1. Western blot analysis of p73 on Hela cell lysates using anti-p73 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-p73 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-p73 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-p73 antibody. Counter stained with hematoxylin. 5. ICC staining p73 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The p53 gene is a widely studied oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents. The p73 isoform p73α inhibits drug-induced apoptosis in small cell lung carcinoma cells, while the p73 isoform p73β promotes it. p73α also prevents Bax activation, mitochondrial dysfunction, caspase activation and is able to reduce apoptosis induced by the BH3-only protein PUMA (p53 upregulated modulator of apoptosis). There is an equilibrium between p73α and p73β, demonstrated by the fact that p73α inhibits the pro-apoptotic effect of p73β. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 70/60(12 isoforms) kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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