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Anti-Cytochrome P450 17A1 Antibody (3S328)

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货号 TMAB-04924

Anti-Cytochrome P450 17A1 Antibody (3S328) 是一种 Rabbit 抗体,靶向 Cytochrome P450 17A1。Anti-Cytochrome P450 17A1 Antibody (3S328) 可用于 WB,ICC/IF,FCM。

Anti-Cytochrome P450 17A1 Antibody (3S328)

Anti-Cytochrome P450 17A1 Antibody (3S328)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04924

Anti-Cytochrome P450 17A1 Antibody (3S328) 是一种 Rabbit 抗体,靶向 Cytochrome P450 17A1。Anti-Cytochrome P450 17A1 Antibody (3S328) 可用于 WB,ICC/IF,FCM。

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50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-Cytochrome P450 17A1 Antibody (3S328) is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Antibody (3S328) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
3S328
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family; it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol.
抗原信息
免疫原
A synthesized peptide: human Cytochrome P450 17A1
抗原种属
Human
基因名称
CYP17A1
基因ID
蛋白名称
Steroid 17-alpha-hydroxylase/17, 20 lyase
Uniprot ID
功能
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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