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Anti-Cytochrome P450 17A1 Antibody (3S328) 是一种 Rabbit 抗体,靶向 Cytochrome P450 17A1。Anti-Cytochrome P450 17A1 Antibody (3S328) 可用于 WB,ICC/IF,FCM。
Anti-Cytochrome P450 17A1 Antibody (3S328) 是一种 Rabbit 抗体,靶向 Cytochrome P450 17A1。Anti-Cytochrome P450 17A1 Antibody (3S328) 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-Cytochrome P450 17A1 Antibody (3S328) is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Antibody (3S328) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 3S328 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family; it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. |
| 免疫原 | A synthesized peptide: human Cytochrome P450 17A1 |
| 抗原种属 | Human |
| 基因名称 | CYP17A1 |
| 基因ID | |
| 蛋白名称 | Steroid 17-alpha-hydroxylase/17, 20 lyase |
| Uniprot ID | |
| 功能 | Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. |
| 分子量 | Theoretical: 57 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |