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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Bim Antibody (4L851)

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货号 TMAB-03148

Anti-Bim Antibody (4L851) 是一种 Rabbit 抗体，靶向 Bim。Anti-Bim Antibody (4L851) 可用于 WB。

Anti-Bim Antibody (4L851)

Anti-Bim Antibody (4L851)

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Rating icon 还可以
货号 TMAB-03148

Anti-Bim Antibody (4L851) 是一种 Rabbit 抗体，靶向 Bim。Anti-Bim Antibody (4L851) 可用于 WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Bim Antibody (4L851) is a Rabbit antibody targeting Bim. Anti-Bim Antibody (4L851) can be used in WB.
Ig Type
IgG
克隆号
4L851
反应种属
Human,Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endomembrane system; Peripheral membrane protein. Note=Associated with intracytoplasmic membranes. Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion.
组织特异性Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Bim, Bcl-2 interacting mediator of cell death, is a pro-apoptotic protein belonging to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. Bim is sequestered in an inactive conformation through binding to the microtubule-associated dynein motor complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibitory binding to anti-apoptotic Bcl-2 family members and subsequent iniation of apoptosis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Bim
抗原种属
Human
基因名称
BCL2L11
基因ID
10018
蛋白名称
Bcl-2-like protein 11
Uniprot ID
O43521
功能
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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