Name: Rezafungin
Brand: TargetMol
SKU: T12732
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 1,480

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2 mg

¥ 2,230

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5 mg

¥ 3,180

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10 mg

¥ 4,660

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25 mg

¥ 7,390

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50 mg

¥ 9,960

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100 mg

¥ 13,300

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1 mL x 10 mM (in DMSO)

¥ 6,490

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产品介绍

生物活性

产品描述	Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.
靶点活性	C. tropicalis:0.03 µg/mL (MIC), C. lusitaniae:0.12 µg/mL (MIC), C. albicans:0.022 µg/mL (MIC), C. guilliermondii:1 µg/mL (MIC), C. insconspicua:0.06 µg/mL (MIC), C. krusei:0.033 µg/Ml (MIC), C. kefyr:0.06 µg/mL (MIC), C. glabrata:0.044 µg/mL (MIC), C. auris:0.153 µg/mL (MIC), C. parapsilosis sensu stricto:1.26 µg/mL (MIC), C. pulcherrima:0.03 µg/mL (MIC), C. dubliniensis:0.06 µg/mL (MIC)
体内活性	小鼠腹腔注射1 mg/kg Rezafungin，每日一次，连续6天的实验结果表明，在C3H/HeN小鼠感染模型中，Rezafungin有效预防Pneumocystis spp.感染，显著降低了核与子囊负荷[1]。
别名	棘白菌素, SP-3025, CD101, Biafungin

化学信息

分子量	1226.39
分子式	C₆₃H₈₅N₈O₁₇
CAS No.	1396640-59-7
Smiles	O=C1N2[C@](C(=O)N[C@H](OCC[N+](C)(C)C)[C@H](O)C[C@H](NC(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CC=C(OCCCCC)C=C5)C(=O)N[C@@]([C@@H](C)O)(C(=O)N6[C@](C(=O)N[C@@]([C@@H]([C@@H](O)C7=CC=C(O)C=C7)O)(C(=O)N[C@]1([C@@H](C)O)[H])[H])(C[C@@H](O)C6)[H])[H])([C@@H](O)[C@@H](C)C2)[H]
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 65 mg/mL (53 mM), Sonication is recommended.

溶液配制表

DMSO

体内实验配液计算器