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Anti-MYBPC3 Antibody (3A577)

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货号 TMAB-09136

Anti-MYBPC3 Antibody (3A577) 是一种 Mouse 抗体，靶向 MYBPC3。Anti-MYBPC3 Antibody (3A577) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-MYBPC3 Antibody (3A577)

Anti-MYBPC3 Antibody (3A577)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09136

Anti-MYBPC3 Antibody (3A577) 是一种 Mouse 抗体，靶向 MYBPC3。Anti-MYBPC3 Antibody (3A577) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MYBPC3 Antibody (3A577) is a Mouse antibody targeting MYBPC3. Anti-MYBPC3 Antibody (3A577) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG1, Kappa
克隆号
3A577
反应种属
Mouse (predicted:Human,Rat)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C. It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle. Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. MYBPC3 binds F-Actin, MHC and native thin filaments, and modifies the activity of Actin-activated myosin ATPase. Mutations in the MYBPC3 gene lead mainly to truncation of the protein, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), a heart disorder characterized by ventricular hypertrophy, which often involves the interventricular septum and is usually asymmetric. The MYBPC3 gene maps to chromosome 11p11.2.
抗原信息
基因名称
MYBPC3
基因ID
4607
蛋白名称
Myosin-binding protein C, cardiac-type
功能
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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