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Anti-Laminin 5 Polyclonal Antibody

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Anti-Laminin 5 Polyclonal Antibody
产品编号 TMAB-01043

Anti-Laminin 5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Laminin 5。Anti-Laminin 5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Laminin 5 Polyclonal Antibody

Anti-Laminin 5 Polyclonal Antibody

Rating icon 还可以
Anti-Laminin 5 Polyclonal Antibody
产品编号 TMAB-01043

Anti-Laminin 5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Laminin 5。Anti-Laminin 5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Laminin 5 Polyclonal Antibody is a Rabbit antibody targeting Laminin 5. Anti-Laminin 5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
验证活性
Tissue/cell: mouse stomach wall; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-Laminin 5 Polyclonal Antibody, Unconjugated (TMAB-01043) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin 5 is an isoform composed of three distinct subunits, alpha 3, beta 3 and gamma 2, which are bound to each other in a cross-shaped molecule by disulphide bonds. It is a complex glycoprotein thought to be involved in cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes. It is also involved in signal transduction via tyrosine phosphorylation of pp125-FAK and p80, and differentiation of keratinocytes. The laminin alpha 3 subunit is also thought to be a component of laminin 6 and laminin 7
抗原信息
免疫原
KLH conjugated synthetic peptide: human LAMA3
抗原种属
Human
基因ID
Uniprot ID
研究领域
Extracellular matrix,Extracellular Matrix,Intermediate Filaments,ECM Proteins,Basal Lamina
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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