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Anti-GITR/TNFRSF18 Antibody (8L457)

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产品编号 TMAY-02615

Anti-GITR/TNFRSF18 Antibody (8L457) 是一种 Rabbit 抗体,靶向 GITR/TNFRSF18。Anti-GITR/TNFRSF18 Antibody (8L457) 可用于 ELISA。

Anti-GITR/TNFRSF18 Antibody (8L457)

Anti-GITR/TNFRSF18 Antibody (8L457)

Rating icon 还可以
产品编号 TMAY-02615

Anti-GITR/TNFRSF18 Antibody (8L457) 是一种 Rabbit 抗体,靶向 GITR/TNFRSF18。Anti-GITR/TNFRSF18 Antibody (8L457) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-GITR/TNFRSF18 Antibody (8L457) is a Rabbit antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8L457) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
8L457
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human GITR/TNFRSF18/CD357 (rh GITR/TNFRSF18/CD357; TMPY-00072; NP_683700.1; Met1-Glu161).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human GITR/TNFRSF18/CD357 Protein (TMPY-00072)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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