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Anti-IL-6R Antibody (5X839)
还可以产品编号 TMAY-03209
Anti-IL-6R Antibody (5X839) 是一种 Rabbit 抗体，靶向 IL-6R。Anti-IL-6R Antibody (5X839) 可用于 ELISA(Cap),FCM。
Anti-IL-6R Antibody (5X839)
Anti-IL-6R Antibody (5X839)
还可以产品编号 TMAY-03209
Anti-IL-6R Antibody (5X839) 是一种 Rabbit 抗体，靶向 IL-6R。Anti-IL-6R Antibody (5X839) 可用于 ELISA(Cap),FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-6R Antibody (5X839) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (5X839) can be used in ELISA(Cap),FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5X839 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse IL6Ra(CD126) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse IL6Ra(CD126), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | ELISA(Cap),FCM |
| 推荐剂量 | FCM: 1:25-1:100; ELISA(Cap): 1:250-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-6R / CD126 (rM IL-6R / CD126; TMPY-01214; NP_034689.2; Ile44-Glu357). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Mouse IL-6R / CD126 protein (TMPY-01214) |
| 抗原种属 | Mouse |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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