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别名 NKH, glycine cleavage system protein H (aminomethyl carrier), GCE
Anti-GCSH Antibody (5C677) 是一种 Rabbit 抗体,靶向 GCSH。Anti-GCSH Antibody (5C677) 可用于 IHC-P。
Anti-GCSH Antibody (5C677) 是一种 Rabbit 抗体,靶向 GCSH。Anti-GCSH Antibody (5C677) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
| 产品描述 | Anti-GCSH Antibody (5C677) is a Rabbit antibody targeting GCSH. Anti-GCSH Antibody (5C677) can be used in IHC-P. |
| 别名 | NKH, glycine cleavage system protein H (aminomethyl carrier), GCE |
| Ig Type | Rabbit IgG |
| 克隆号 | 5C677 |
| 交叉反应 | Human |
| 特异性 | Human GCSH |
| 验证活性 | 1. Immunochemical staining of human GCSH in human kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human GCSH in human liver with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human GCSH (rh GCSH; TMPY-03503; AAA36011.1; Ser49-Glu173). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for GCSH gene. Also, several transcribed and non-transcribed pseudogenes of GCSH gene exist throughout the genome. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human GCSH Protein (TMPY-03503) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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