购物车
- 全部删除
您的购物车当前为空
GSK2646264
还可以
产品编号 T61527Cas号 1398695-47-0
GSK2646264 (Compound 44) is a highly effective and specific inhibitor of spleen tyrosine kinase (SYK) with a pIC50 of 7.1. In addition to targeting SYK, GSK2646264 also inhibits several other kinases, including LCK, LRRK2, GSK3β, JAK2, VEGFR2, Aurora B, and Aurora A, with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, <4.6 and <4.3, respectively. Notably, GSK2646264 demonstrates skin penetrability, reaching both the epidermis and dermis [1].
GSK2646264
还可以产品编号 T61527Cas号 1398695-47-0
GSK2646264 (Compound 44) is a highly effective and specific inhibitor of spleen tyrosine kinase (SYK) with a pIC50 of 7.1. In addition to targeting SYK, GSK2646264 also inhibits several other kinases, including LCK, LRRK2, GSK3β, JAK2, VEGFR2, Aurora B, and Aurora A, with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, <4.6 and <4.3, respectively. Notably, GSK2646264 demonstrates skin penetrability, reaching both the epidermis and dermis [1].
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 18,995 | 8-10周 | |
| 50 mg | ¥ 28,484 | 8-10周 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
GSK2646264 相关产品
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)GSK3B Protein, Human, Recombinant (His)VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)VEGFR2/KDR Protein, Human, Recombinant (His)VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), BiotinylatedVEGFR3/FLT4 Protein, Human, Recombinant (His)GSK3B Protein, Human, Recombinant (E. coli, His)VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)JAK2 Protein, Human, Recombinant (His)FGL1 Protein, Mouse, Recombinant (hFc)VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
View More 联系我们获取更多批次信息
资源下载
产品介绍
生物活性
化学信息
| 产品描述 | GSK2646264 (Compound 44) is a highly effective and specific inhibitor of spleen tyrosine kinase (SYK) with a pIC50 of 7.1. In addition to targeting SYK, GSK2646264 also inhibits several other kinases, including LCK, LRRK2, GSK3β, JAK2, VEGFR2, Aurora B, and Aurora A, with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, <4.6 and <4.3, respectively. Notably, GSK2646264 demonstrates skin penetrability, reaching both the epidermis and dermis [1]. |
| 靶点活性 | LCK:5.4 (pIC50), Aurora B:<4.6 (pIC50), LRRK2:5.4 (pIC50), VEGFR2:4.5 (pIC50), JAK2:5 (pIC50), Syk:7.1 (pIC50), GSK-3β:5.3 (pIC50), Aurora A:<4.3 (pIC50) |
| 分子量 | 374.48 |
| 分子式 | C24H26N2O2 |
| CAS No. | 1398695-47-0 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 一共给药动物 10 只 ，您使用的配方为 5% 
DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为 2 mg/mL 。 体内配方的制备方法: 取 50μLDMSO 母液，添加 300 μLPEG300 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH2O 混匀澄清
母液，添加 300 μLPEG300 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH2O 混匀澄清 以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
SCI 文献
评论列表
预览
Related Tags: buy GSK2646264 | purchase GSK2646264 | GSK2646264 cost | order GSK2646264 | GSK2646264 chemical structure | GSK2646264 formula | GSK2646264 molecular weight
嗨！有任何问题？点我咨询
评论内容