购物车
- 全部删除
您的购物车当前为空
Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384)
还可以产品编号 TMAY-01395C
Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) 是一种 PerCP-conjugated Mouse 抗体，靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) 可用于 FCM。
Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384)
Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384)
还可以产品编号 TMAY-01395C
Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) 是一种 PerCP-conjugated Mouse 抗体，靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) 可用于 FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) is a PerCP-conjugated Mouse antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 6O384 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD3 expression on human peripheral blood lymphocytes. Cells were stained with PerCP-conjugated anti-Human CD3 and APC conjugated anti-Human CD19 (BD Pharmingen™ Cat. No. 555415). The dot plots were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | T-cell surface glycoprotein CD3 epsilon chain, also known as CD3E, is a single-pass type I membrane protein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. The CD3 epsilon subunit of the T cell receptor (TCR) complex contains two defined signaling domains, a proline-rich sequence and an immune tyrosine activation motifs (ITAMs), and this complex undergoes a conformational change upon ligand binding that is thought to be important for the activation of T cells. In the CD3 epsilon mutant mice, all stages of T cell development and activation that are TCR-dependent were impaired, but not eliminated, including activation of mature naïve T cells with the MHCII presented superantigen, staphylococcal enterotoxin B, or with a strong TCR cross-linking antibody specific for either TCR-Cbeta or CD3 epsilon. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. Homozygous mutations in CD3D and CD3E genes lead to a complete block in T-cell development and thus to an early-onset severe combined immunodeficiency phenotype.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | PerCP |
| 其他可选修饰符 | Unconjugated/APC/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human CD3e / CD3 epsilon protein (TMPY-01191) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) | purchase Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) | Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384) cost | order Anti-CD3 epsilon/CD3e Antibody-PerCP (6O384)
嗨！有任何问题？点我咨询
评论内容