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Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
别名 Ragulator Complex Protein LAMTOR3, Mp1, Mitogen-Activated Protein Kinase Scaffold Protein 1, Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1, MEK-Binding Partner 1, M, Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3, LAMTOR3
Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 693 | 2-4周 | |
| 10 μg | ¥ 1,170 | 2-4周 | |
| 20 μg | ¥ 1,860 | 2-4周 | |
| 50 μg | ¥ 3,470 | 2-4周 | |
| 100 μg | ¥ 4,930 | 2-4周 | |
| 200 μg | ¥ 7,350 | 2-4周 | |
| 500 μg | ¥ 12,100 | 2-4周 | |
| 1 mg | ¥ 17,300 | 2-4周 |
| 产品描述 | Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-6xHis |
| 蛋白编号 | Q9UHA4 |
| 氨基酸序列 | Met1-Ser124 |
| 蛋白构建 | Met1-Ser124 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 5 mM DTT, 30% Glycerol, pH 8.0. |
| 别名 | Ragulator Complex Protein LAMTOR3, Mp1, Mitogen-Activated Protein Kinase Scaffold Protein 1, Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1, MEK-Binding Partner 1, M, Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3, LAMTOR3 |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 15 KDa (reducing condition) |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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