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Anti-Thioredoxin/TRX Antibody (5F422)
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产品编号 TMAC-04031
别名 TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Anti-Thioredoxin/TRX Antibody (5F422) 是一种 Rabbit 抗体，靶向 Thioredoxin/TRX。Anti-Thioredoxin/TRX Antibody (5F422) 可用于 WB,ICC/IF,IHC,IP。
Anti-Thioredoxin/TRX Antibody (5F422)
Anti-Thioredoxin/TRX Antibody (5F422)
还可以产品编号 TMAC-04031 别名 TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Anti-Thioredoxin/TRX Antibody (5F422) 是一种 Rabbit 抗体，靶向 Thioredoxin/TRX。Anti-Thioredoxin/TRX Antibody (5F422) 可用于 WB,ICC/IF,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Thioredoxin/TRX Antibody (5F422) is a Rabbit antibody targeting Thioredoxin/TRX. Anti-Thioredoxin/TRX Antibody (5F422) can be used in WB,ICC/IF,IHC,IP. |
| 别名 | TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of TRX1 on different lysates using anti-TRX1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Human lung. 2. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-TRX1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-TRX1 antibody. Counter stained with hematoxylin. 4. ICC staining TRX1 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining TRX1 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining TRX1 in SKOV-3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:100-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 12 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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