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Anti-CD4 Polyclonal Antibody 4

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货号 TMAB-03980

Anti-CD4 Polyclonal Antibody 4 是一种 Rabbit 抗体，靶向 CD4。Anti-CD4 Polyclonal Antibody 4 可用于 WB。

Anti-CD4 Polyclonal Antibody 4

Anti-CD4 Polyclonal Antibody 4

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Rating icon 还可以
货号 TMAB-03980

Anti-CD4 Polyclonal Antibody 4 是一种 Rabbit 抗体，靶向 CD4。Anti-CD4 Polyclonal Antibody 4 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD4 Polyclonal Antibody 4 is a Rabbit antibody targeting CD4. Anti-CD4 Polyclonal Antibody 4 can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
Sample:
Spleen (Rat) Lysate at 40 μg
Spleen (Mouse) Lysate at 40 μg
Lymph node (Rat) Lysate at 40 μg
Lymph node (Mouse) Lysate at 40 μg
Thymus (Rat) Lysate at 40 μg
Thymus (Mouse) Lysate at 40 μg
Small intestine (Rat) Lysate at 40 μg
Small intestine (Mouse) Lysate at 40 μg
Large intestine (Rat) Lysate at 40 μg
Large intestine (Mouse) Lysate at 40 μg
HL60 (Human) Cell Lysate at 30 μg
Jurkat (Human) Cell Lysate at 30 μg
Primary: Anti-CD4 (TMAB-03980) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 52 kD
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD4
抗原种属
Human
基因名称
CD4
基因ID
920
蛋白名称
T-cell surface glycoprotein CD4
Uniprot ID
P01730
功能
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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