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Anti-CD59a Antibody (6N524) 是一种 Rabbit 抗体,靶向 CD59a。Anti-CD59a Antibody (6N524) 可用于 ELISA。
Anti-CD59a Antibody (6N524) 是一种 Rabbit 抗体,靶向 CD59a。Anti-CD59a Antibody (6N524) 可用于 ELISA。
产品描述 | Anti-CD59a Antibody (6N524) is a Rabbit antibody targeting CD59a. Anti-CD59a Antibody (6N524) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6N524 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD59a / Protectin (rM CD59a / Protectin; TMPY-02266; NP_001104530.1; Met1-Lys95). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins. It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse CD59a / Protectin Protein (TMPY-02266) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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