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Anti-Cathelicidin/Camp Polyclonal Antibody

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Anti-Cathelicidin/Camp Polyclonal Antibody
产品编号 TMAB-00296
别名 LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein

Anti-Cathelicidin/Camp Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cathelicidin/Camp。Anti-Cathelicidin/Camp Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-Cathelicidin/Camp Polyclonal Antibody

Anti-Cathelicidin/Camp Polyclonal Antibody

Rating icon 还可以
Anti-Cathelicidin/Camp Polyclonal Antibody
产品编号 TMAB-00296 别名 LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein

Anti-Cathelicidin/Camp Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cathelicidin/Camp。Anti-Cathelicidin/Camp Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
别名LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein
Ig Type
IgG
交叉反应
(predicted:Mouse,Rat)
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. FALL-39 precursor (FALL-39 peptide antibiotic, cationic anti-microbial protein, CAMP, CAP-18, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170). In contrast to the defensins, which are cysteine-rich peptides that fold in ∫-pleated sheets, LL-37 is a cysteine-free peptide that can adopt an amphipathic å-helical conformation. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils. The mouse and rat ortholog, CRAMP (cathelin-related antimicrobial peptide), is also part of the cathelicidin family of host defense peptides. These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair. CRAMP is expressed in testis, spleen, stomach and intestine. This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2021]
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Camp
抗原种属
Mouse
基因ID
Uniprot ID
研究领域
cAMP
化学信息
分子量Theoretical: 19 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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