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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CASP8 Monoclonal Antibody (8Z123)

Synonyms: MGC78473, MCH5, MACH, FLJ17672, FLICE, Casp-8, CAP4, ALPS2B
货号 TMAT-0211 一键复制产品信息
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Anti-CASP8 Monoclonal Antibody (8Z123) 是一种 Mouse 抗体，靶向 CASP8。Anti-CASP8 Monoclonal Antibody (8Z123) 可用于 WB,IHC,FCM。

Anti-CASP8 Monoclonal Antibody (8Z123)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0211

别名 MGC78473, MCH5, MACH, FLJ17672, FLICE, Casp-8, CAP4, ALPS2B

Anti-CASP8 Monoclonal Antibody (8Z123) 是一种 Mouse 抗体，靶向 CASP8。Anti-CASP8 Monoclonal Antibody (8Z123) 可用于 WB,IHC,FCM。

Anti-CASP8 Monoclonal Antibody (8Z123)
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产品介绍

生物活性
产品描述
Anti-CASP8 Monoclonal Antibody (8Z123) is a Mouse antibody targeting CASP8. Anti-CASP8 Monoclonal Antibody (8Z123) can be used in WB,IHC,FCM.
别名
MGC78473, MCH5, MACH, FLJ17672, FLICE, Casp-8, CAP4, ALPS2B
Ig Type
IgG1
克隆号
8Z123
反应种属
Human,Mouse,Monkey,Rat
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CASP8 expressed in E. Coli.
抗原种属
Human
基因名称
CASP8
基因ID
841
蛋白名称
Caspase-8
Uniprot ID
Q14790
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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