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Anti-OAT-3 Polyclonal Antibody

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Anti-OAT-3 Polyclonal Antibody
产品编号 TMAB-01279

Anti-OAT-3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OAT-3。Anti-OAT-3 Polyclonal Antibody 可用于 WB。

Anti-OAT-3 Polyclonal Antibody

Anti-OAT-3 Polyclonal Antibody

Rating icon 还可以
Anti-OAT-3 Polyclonal Antibody
产品编号 TMAB-01279

Anti-OAT-3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OAT-3。Anti-OAT-3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-OAT-3 Polyclonal Antibody is a Rabbit antibody targeting OAT-3. Anti-OAT-3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat,Rabbit)
验证活性
Sample: Kidney (Mouse) Lysate at 40 μg
Primary: Anti-OAT-3 (TMAB-01279) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 59 kDa
Observed band size: 65 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Basolateral cell membrane; Multi-pass membrane protein (Potential). Note=Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Human organic anion transporter (OAT) 3 (SLC22A8) is localized to the basolateral membranes of renal tubular epithelial cells and plays a critical role in the excretion of anionic compounds. Recent advances in molecular biology have identified three organic anion transporter families: the organic anion transporter (OAT) family encoded by SLC22A, the organic anion transporting peptide (OATP) family encoded by SLC21A (SLCO), and the multidrug resistance-associated protein (MRP) family encoded by ABCC. These families play critical roles in the transepithelial transport of organic anions in the kidneys as well as in other tissues such as the liver and brain. Among these families, the OAT family plays the central role in renal organic anion transport. Knowledge of these three families at the molecular level, such as substrate selectivity, tissue distribution, and gene localization, is rapidly increasing.
抗原信息
免疫原
KLH conjugated synthetic peptide: rat OAT-3
抗原种属
Rat
研究领域
Channels,Drug metabolism,Drug metabolism
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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