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Anti-NEDD5/septin 2 Antibody (2M904) 是一种 Rabbit 抗体,靶向 NEDD5/septin 2。Anti-NEDD5/septin 2 Antibody (2M904) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。
Anti-NEDD5/septin 2 Antibody (2M904) 是一种 Rabbit 抗体,靶向 NEDD5/septin 2。Anti-NEDD5/septin 2 Antibody (2M904) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-NEDD5/septin 2 Antibody (2M904) is a Rabbit antibody targeting NEDD5/septin 2. Anti-NEDD5/septin 2 Antibody (2M904) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM. |
| Ig Type | IgG |
| 克隆号 | 2M904 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrICC/IFIFIPFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cytoplasm, cell cortex. |
| 组织特异性 | Widely expressed. Up-regulated in liver cancer. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation |
| 免疫原 | A synthesized peptide: human Septin 2 |
| 抗原种属 | Human |
| 基因名称 | SEPTIN2 |
| 基因ID | |
| 蛋白名称 | Septin-2 |
| Uniprot ID | |
| 功能 | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. |
| 分子量 | Theoretical: 41 kDa. Actual: 41 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |