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Anti-Siglec-5 Antibody-FITC (3K993)

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产品编号 TMAY-02066F

Anti-Siglec-5 Antibody-FITC (3K993) 是一种 FITC-conjugated Rabbit 抗体,靶向 Siglec-5。Anti-Siglec-5 Antibody-FITC (3K993) 可用于 FCM。

Anti-Siglec-5 Antibody-FITC (3K993)

Anti-Siglec-5 Antibody-FITC (3K993)

Rating icon 还可以
产品编号 TMAY-02066F

Anti-Siglec-5 Antibody-FITC (3K993) 是一种 FITC-conjugated Rabbit 抗体,靶向 Siglec-5。Anti-Siglec-5 Antibody-FITC (3K993) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-Siglec-5 Antibody-FITC (3K993) is a FITC-conjugated Rabbit antibody targeting Siglec-5. Anti-Siglec-5 Antibody-FITC (3K993) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
3K993
交叉反应
Human
验证活性
Flow cytometric analysis of Human SIGLEC5(CD170) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human SIGLEC5(CD170). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
应用
FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SIGLEC5 (rh SIGLEC5; TMPY-03549; O15389; Met1-Thr 434) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Human SIGLEC5 Protein (TMPY-03549)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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