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Anti-Phospho-Kir6.2 (Thr224) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Kir6.2 (Thr224)。Anti-Phospho-Kir6.2 (Thr224) Polyclonal Antibody 可用于 WB,IF。
Anti-Phospho-Kir6.2 (Thr224) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Kir6.2 (Thr224)。Anti-Phospho-Kir6.2 (Thr224) Polyclonal Antibody 可用于 WB,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-Kir6.2 (Thr224) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Kir6.2 (Thr224). Anti-Phospho-Kir6.2 (Thr224) Polyclonal Antibody can be used in WB,IF. |
别名 | p-Kir6.2 (Thr224), p-Kir6.2 (T224), Kir6.2 (p-Thr224), Kir6.2 (p-T224) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from HeLa cells, using Kir6.2 (Phospho-Thr224) antibody TMAC-02323. The lane on the right is treated with the synthesized peptide. 2. Immunofluorescence analysis of HuvEc cells, using Kir6.2 (Phospho-Thr224) antibody TMAC-02323. The picture on the right is treated with the synthesized peptide. |
应用 | |
推荐剂量 | WB: 1:500-3000; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium By similarity. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 224 (K-T-TP-S-P) derived from Human Kir62 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 40 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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