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Anti-ALK-1 Antibody (3T59)

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货号 TMAY-00210

别名 ACVRL1, activin A receptor type II-like 1

Anti-ALK-1 Antibody (3T59) 是一种 Rabbit 抗体,靶向 ALK-1。Anti-ALK-1 Antibody (3T59) 可用于 IP,WB。

Anti-ALK-1 Antibody (3T59)

Anti-ALK-1 Antibody (3T59)

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货号 TMAY-00210 别名 ACVRL1, activin A receptor type II-like 1

Anti-ALK-1 Antibody (3T59) 是一种 Rabbit 抗体,靶向 ALK-1。Anti-ALK-1 Antibody (3T59) 可用于 IP,WB。

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100 μL
¥ 2,279
5日内发货
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产品介绍


生物活性
产品描述
Anti-ALK-1 Antibody (3T59) is a Rabbit antibody targeting ALK-1. Anti-ALK-1 Antibody (3T59) can be used in IP,WB.
别名ACVRL1, activin A receptor type II-like 1
Ig Type
Rabbit IgG
克隆号
3T59
反应种属
Human
特异性
Human ALK-1
验证活性
1. ALK1 was immunoprecipitated using:
-Lane A:0.5 mg MCF-7 Whole Cell Lysate.
-Lane B:0.5 mg K562 Whole Cell Lysate.
-2 µL anti-ALK1 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose.
-Primary antibody:
-Anti-ALK1 rabbit monoclonal antibody, at 1:100 dilution.
-Secondary antibody:
-Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution.
-Developed using the odyssey technique.
-Performed under reducing conditions.
-Predicted band size: 56 kDa.
-Observed band size: 56 kDa.
2. Anti-ALK1 rabbit monoclonal antibody at 1:500 dilution.
-Lane A: MCF7 Whole Cell Lysate.
-Lane B: K562 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:56 kDa.
-Observed band size:41 kDa
应用IPWB
推荐剂量
WB: 1:500-1:2000; IP: 1-4 μL/mg of lysate
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ALK-1 / ACVRL1 (rh ALK-1 / ACVRL1; TMPY-01168; NP_000011.2; Met1-Gln118).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human ALK-1 / ACVRL1 protein (TMPY-01168)
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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