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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MBNL1 Antibody (9Q820)

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货号 TMAB-08646

Anti-MBNL1 Antibody (9Q820) 是一种 Rabbit 抗体，靶向 MBNL1。Anti-MBNL1 Antibody (9Q820) 可用于 FCM。

Anti-MBNL1 Antibody (9Q820)

Anti-MBNL1 Antibody (9Q820)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08646

Anti-MBNL1 Antibody (9Q820) 是一种 Rabbit 抗体，靶向 MBNL1。Anti-MBNL1 Antibody (9Q820) 可用于 FCM。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-MBNL1 Antibody (9Q820) is a Rabbit antibody targeting MBNL1. Anti-MBNL1 Antibody (9Q820) can be used in FCM.
Ig Type
IgG
克隆号
9Q820
反应种属
Human (predicted:Mouse)
应用FCM
推荐剂量
FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cytoplasmic granule. Localized with DDX1, TIAL1 and YBX1 in stress granules upon stress. Localized in the cytoplasm of multinucleated myotubes. Colocalizes with nuclear foci of retained expanded-repeat transcripts in myotubes from patients affected by myotonic dystrophy.
组织特异性Highly expressed in cardiac, skeletal muscle and during myoblast differentiation. Weakly expressed in other tissues (at protein level). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA.
抗原信息
免疫原
A synthesized peptide: human MBNL1
抗原种属
Human
基因名称
MBNL1
基因ID
4154
蛋白名称
Muscleblind-like protein 1
Uniprot ID
Q9NR56
功能
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
化学信息
分子量Theoretical: 42 kDa. Actual: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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