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Anti-JAM-A Antibody (5G304)
还可以产品编号 TMAY-00439
Anti-JAM-A Antibody (5G304) 是一种 Mouse 抗体，靶向 JAM-A。Anti-JAM-A Antibody (5G304) 可用于 ELISA,ELISA(Det)。
Anti-JAM-A Antibody (5G304)
Anti-JAM-A Antibody (5G304)
还可以产品编号 TMAY-00439
Anti-JAM-A Antibody (5G304) 是一种 Mouse 抗体，靶向 JAM-A。Anti-JAM-A Antibody (5G304) 可用于 ELISA,ELISA(Det)。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-JAM-A Antibody (5G304) is a Mouse antibody targeting JAM-A. Anti-JAM-A Antibody (5G304) can be used in ELISA,ELISA(Det). |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 5G304 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Det) |
| 推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A extracellular domain (rh JAM-A; TMPY-01035; Met 1-Ala 242; NP_058642.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human JAM-A protein (TMPY-01035) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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