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Anti-ENPP7 Antibody (6N785)

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产品编号 TMAY-01286

Anti-ENPP7 Antibody (6N785) 是一种 Rabbit 抗体,靶向 ENPP7。Anti-ENPP7 Antibody (6N785) 可用于 ELISA。

Anti-ENPP7 Antibody (6N785)

Anti-ENPP7 Antibody (6N785)

Rating icon 还可以
产品编号 TMAY-01286

Anti-ENPP7 Antibody (6N785) 是一种 Rabbit 抗体,靶向 ENPP7。Anti-ENPP7 Antibody (6N785) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-ENPP7 Antibody (6N785) is a Rabbit antibody targeting ENPP7. Anti-ENPP7 Antibody (6N785) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
6N785
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ENPP7 / NPP-7 (rh ENPP7; TMPY-01070; NP_848638.2; Met 1-Ser 439).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I membrane protein which belongs to thenucleotide pyrophosphatase / phosphodiesterase family. ENPP7 / NPP-7 is expressed in the intestines and human bile. ENPP7 / NPP-7 is localized at the surface of the microvillar membrane in small intestine enterocytes, as well as in endosome-like structures and in Golgi complex. The main function of ENPP7 / NPP-7 is to convert the dietary sphingomyelin into ceramide, the sphingolipid messengers via hydrolyzation. ENPP7 / NPP-7 is also reported to exert a phospholipase C activity toward palmitoyl lyso-phosphocholine. The activity of this enzyme is inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Further, It has been shown in studies that decreased levels of ENPP7 / NPP-7 may be associated with human colon cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human ENPP7 protein (TMPY-01070)
抗原种属
Human
研究领域
Phosphatases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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