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Anti-ENPP7 Antibody (6N785) 是一种 Rabbit 抗体,靶向 ENPP7。Anti-ENPP7 Antibody (6N785) 可用于 ELISA。
Anti-ENPP7 Antibody (6N785) 是一种 Rabbit 抗体,靶向 ENPP7。Anti-ENPP7 Antibody (6N785) 可用于 ELISA。
产品描述 | Anti-ENPP7 Antibody (6N785) is a Rabbit antibody targeting ENPP7. Anti-ENPP7 Antibody (6N785) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6N785 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ENPP7 / NPP-7 (rh ENPP7; TMPY-01070; NP_848638.2; Met 1-Ser 439). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I membrane protein which belongs to thenucleotide pyrophosphatase / phosphodiesterase family. ENPP7 / NPP-7 is expressed in the intestines and human bile. ENPP7 / NPP-7 is localized at the surface of the microvillar membrane in small intestine enterocytes, as well as in endosome-like structures and in Golgi complex. The main function of ENPP7 / NPP-7 is to convert the dietary sphingomyelin into ceramide, the sphingolipid messengers via hydrolyzation. ENPP7 / NPP-7 is also reported to exert a phospholipase C activity toward palmitoyl lyso-phosphocholine. The activity of this enzyme is inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Further, It has been shown in studies that decreased levels of ENPP7 / NPP-7 may be associated with human colon cancer. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ENPP7 protein (TMPY-01070) |
抗原种属 | Human |
研究领域 | Phosphatases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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